USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q13509 USC-OGP 2-DE database:  Q13509 Q13509 General information about the entry View entry in simple text format Entry name TBB3_HUMAN Primary accession number Q13509 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III;. Gene name Name=TUBB3 Synonyms=TUBB4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0224: pI=5.01; Mw=20501 Cross-references UniProtKB/Swiss-Prot Q13509; TBB3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TBB3_HUMAN Primary accession number Q13509 Secondary accession number(s) A8K854 Q9BTZ0 Q9BW10 Sequence was last modified on  May 2, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 167) Name and origin of the protein Description RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III; Gene name Name=TUBB3 Synonyms=TUBB4 Encoded on Name=TUBB3; Synonyms=TUBB4 Keywords 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Disease mutation; GTP-binding; Isopeptide bond; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U47634; AAC52035.1; -; mRNA EMBL AF427491; AAL28094.1; -; mRNA EMBL AK122757; BAG53710.1; -; mRNA EMBL AK292219; BAF84908.1; -; mRNA EMBL AC092143; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471184; EAW66674.1; -; Genomic_DNA EMBL BC000748; AAH00748.1; -; mRNA EMBL BC003021; AAH03021.2; -; mRNA CCDS CCDS10988.1; -. [Q13509-1]; . CCDS CCDS56012.1; -. [Q13509-2]; . RefSeq NP_001184110.1; NM_001197181.1. [Q13509-2]; . RefSeq NP_006077.2; NM_006086.3. [Q13509-1]; . UniGene Hs.511743; -; . PDB 5IJ0; EM; 3.80 A; B=1-426 PDB 5IJ9; EM; 3.70 A; B=1-426 PDB 5JCO; EM; 4.00 A; C/D/I/J/K/L=1-426 PDBsum 5IJ0; -; . PDBsum 5IJ9; -; . PDBsum 5JCO; -; . ProteinModelPortal Q13509; -; . SMR Q13509; -; . BioGrid 115654; 206; . DIP DIP-31505N; -; . IntAct Q13509; 139; . MINT MINT-1163245; -; . STRING 9606.ENSP00000320295; -; . ChEMBL CHEMBL2597; -; . DrugBank DB05147; CYT997; . DrugBank DB03010; Epothilone B; . DrugBank DB01873; Epothilone D; . DrugBank DB04845; Ixabepilone; . DrugBank DB06042; ZEN-012; . GuidetoPHARMACOLOGY 2752; -; . iPTMnet Q13509; -; . PhosphoSitePlus Q13509; -; . SwissPalm Q13509; -; . BioMuta TUBB3; -; . DMDM 20455526; -; . OGP Q13509; -; . EPD Q13509; -; . MaxQB Q13509; -; . PaxDb Q13509; -; . PeptideAtlas Q13509; -; . PRIDE Q13509; -; . TopDownProteomics Q13509-1; -. [Q13509-1]; . DNASU 10381; -; . Ensembl ENST00000315491; ENSP00000320295; ENSG00000258947. [Q13509-1]; . Ensembl ENST00000554444; ENSP00000451617; ENSG00000258947. [Q13509-2]; . GeneID 10381; -; . KEGG hsa:10381; -; . UCSC uc002fph.2; human. [Q13509-1]; . CTD 10381; -; . DisGeNET 10381; -; . GeneCards TUBB3; -; . GeneReviews TUBB3; -; . HGNC HGNC:20772; TUBB3; . HPA HPA043640; -; . HPA HPA046280; -; . MalaCards TUBB3; -; . MIM 600638; phenotype; . MIM 602661; gene; . MIM 614039; phenotype; . neXtProt NX_Q13509; -; . OpenTargets ENSG00000258947; -; . Orphanet 45358; Congenital fibrosis of extraocular muscles; . Orphanet 300570; Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation; . PharmGKB PA134953867; -; . eggNOG KOG1375; Eukaryota; . eggNOG COG5023; LUCA; . GeneTree ENSGT00760000119061; -; . HOGENOM HOG000165710; -; . HOVERGEN HBG000089; -; . InParanoid Q13509; -; . KO K07375; -; . OrthoDB EOG091G06U2; -; . PhylomeDB Q13509; -; . TreeFam TF300298; -; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-190840; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; . Reactome R-HSA-190861; Gap junction assembly; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-380320; Recruitment of NuMA to mitotic centrosomes; . Reactome R-HSA-389957; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-389977; Post-chaperonin tubulin folding pathway; . Reactome R-HSA-437239; Recycling pathway of L1; . Reactome R-HSA-5610787; Hedgehog 'off' state; . Reactome R-HSA-5617833; Cilium Assembly; . Reactome R-HSA-5620924; Intraflagellar transport; . Reactome R-HSA-5626467; RHO GTPases activate IQGAPs; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811434; COPI-dependent Golgi-to-ER retrograde traffic; . Reactome R-HSA-6811436; COPI-independent Golgi-to-ER retrograde traffic; . Reactome R-HSA-68877; Mitotic Prometaphase; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-983189; Kinesins; . SIGNOR Q13509; -; . ChiTaRS TUBB3; human; . GeneWiki TUBB3; -; . GenomeRNAi 10381; -; . PRO PR:Q13509; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000258947; -; . CleanEx HS_TUBB3; -; . CleanEx HS_TUBB4; -; . ExpressionAtlas Q13509; baseline and differential; . Genevisible Q13509; HS; . GO GO:0030424; C:axon; IEA:Ensembl; . GO GO:0071944; C:cell periphery; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; IEA:UniProtKB-KW; . GO GO:0030425; C:dendrite; ISS:ParkinsonsUK-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0015630; C:microtubule cytoskeleton; IDA:HPA; . GO GO:0043025; C:neuronal cell body; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IEA:InterPro; . GO GO:0042277; F:peptide binding; IEA:Ensembl; . GO GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro; . GO GO:0007411; P:axon guidance; IMP:UniProtKB; . GO GO:0007017; P:microtubule-based process; IEA:InterPro; . GO GO:0007067; P:mitotic nuclear division; IEA:Ensembl; . Gene3D 1.10.287.600; -; 1; . Gene3D 3.30.1330.20; -; 1; . Gene3D 3.40.50.1440; -; 1; . InterPro IPR013838; Beta-tubulin_BS; . InterPro IPR002453; Beta_tubulin; . InterPro IPR008280; Tub_FtsZ_C; . InterPro IPR000217; Tubulin; . InterPro IPR018316; Tubulin/FtsZ_2-layer-sand-dom; . InterPro IPR023123; Tubulin_C; . InterPro IPR017975; Tubulin_CS; . InterPro IPR003008; Tubulin_FtsZ_GTPase; . PANTHER PTHR11588; PTHR11588; 1; . Pfam PF00091; Tubulin; 1; . Pfam PF03953; Tubulin_C; 1; . PRINTS PR01163; BETATUBULIN; . PRINTS PR01161; TUBULIN; . SMART SM00864; Tubulin; 1; . SMART SM00865; Tubulin_C; 1; . SUPFAM SSF52490; SSF52490; 1; . SUPFAM SSF55307; SSF55307; 1; . PROSITE PS00227; TUBULIN; 1; . PROSITE PS00228; TUBULIN_B_AUTOREG; 1; .

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